PathMap Literature Based Discovery Engine

Share your Discovery:

Guaranteed to find unpublished literature based discoveries.

Clear Search

Experiment #00000141

Hypothesis: Repurposing IVF screening tools to verify CRISPR-corrected induced pluripotent stem cells (iPSCs), combined with in vitro gametogenesis, may potentially create disease-free germlines that could eradicate heritable hematological mutations in future generations, such as sickle cell disease.

CRISPR-Cas Systems _gates_from_crispr_cas_systems Induced Pluripotent Stem Cells _gates_to_induced_pluripotent_stem_cells _gates_from_induced_pluripotent_stem_cells Anemia, Sickle Cell _gates_to_anemia__sickle_cell
View Results
Experiment #00000080

Prenatal iron deficiency (ID) exacerbates the risk of sudden infant death syndrome (SIDS) by modulating the expression of the hypothalamic orexin system, impairing homeostatic arousal mechanisms during hypoxia.

Anemia, Iron-Deficiency _gates_from_anemia__iron_deficiency Hypothalamic-Hypophyseal System _gates_to_hypothalamic_hypophyseal_system _gates_from_hypothalamic_hypophyseal_system Sudden Infant Death _gates_to_sudden_infant_death _gates_from_sudden_infant_death Orexins _gates_to_orexins
View Results