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Experiment #00000130

Targeted alteration of the oral microbiome via a single polyphenol- and fiber-dense meal plan creates an immediate shift in the microbial composition of involuntary nocturnal microaspiration droplets. Upon entry into the lower respiratory tract, this eubiotic bacterial influx acts as an acute molecular signal that rapidly modulates microglia reactivity and neuroinflammation via the lung-brain axis, bypassing systemic colonic metabolite transport.

Dietary modification _gates_from_dietary_modification Dysbiosis _gates_to_dysbiosis _gates_from_dysbiosis Respiratory Aspiration _gates_to_respiratory_aspiration _gates_from_respiratory_aspiration Microglia _gates_to_microglia
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Experiment #00000118

Environmental plant-derived extracellular vesicles (such as those from pollen or agricultural dust) may act as stealth vectors via nasal-olfactory pathways, potentially delivering environmental toxins or pathogenic RNAs that bypass the BBB and trigger neurodegenerative pathologies, such as Amyotrophic Lateral Sclerosis.

Olfactory Pathways _gates_from_olfactory_pathways Extracellular Vesicles _gates_to_extracellular_vesicles _gates_from_extracellular_vesicles Biological Factors _gates_to_biological_factors _gates_from_biological_factors Amyotrophic Lateral Sclerosis _gates_to_amyotrophic_lateral_sclerosis
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Experiment #00000081

How does the gut microbiome modulate inflammation?

Microbial Dysbiosis _gates_from_microbial_dysbiosis Permeability _gates_to_permeability _gates_from_permeability Bacterial Translocation _gates_to_bacterial_translocation _gates_from_bacterial_translocation Toll-Like Receptor 4 _gates_to_toll_like_receptor_4
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Experiment #00000033

Acinetobacter baumannii and Pseudomonas may share pathways with other pathologies and there may be therapeutic bacteriophages or other non-antibiotic solutions hidden with in PubMed literature.

Drug Resistance, Multiple, Bacterial _gates_from_drug_resistance__multiple__bacterial Anti-Bacterial Agents _gates_to_anti_bacterial_agents Multidrug resistance _gates_from_multidrug_resistance Therapeutics _gates_to_therapeutics Biofilms _gates_from_biofilms
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Experiment #00000026

Can post-lyme disease syndrome be cured?

Lyme Disease _gates_from_lyme_disease Anti-Bacterial Agents _gates_to_anti_bacterial_agents _gates_from_anti_bacterial_agents Post-Treatment Lyme Disease Syndrome _gates_to_post_treatment_lyme_disease_syndrome _gates_from_post_treatment_lyme_disease_syndrome 10-20% of cases _gates_to_10_20__of_cases
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