PathMap Literature Based Discovery Engine

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Experiment #00000134

Hypothesis: Intraperitoneal administration of a thermoresponsive hydrogel loaded with borneol-functionalized ginger derived extracellular vesicles (Moxibustion-Modified GDEVs) may provide a sustained, localized delivery to ovarian tumors, potentially enhancing deep tissue penetration and inducing apoptosis without systemic chemotoxicity.

Extracellular Vesicles _gates_from_extracellular_vesicles Nanocarriers _gates_to_nanocarriers Hydrogels _gates_to_hydrogels _gates_from_hydrogels Delayed-Action Preparations _gates_to_delayed_action_preparations Borneol/GEVs

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Experiment #00000073

Can botulinum toxin A (BTX-A) be repurposed from cosmetic/spasticity applications in order to treat oculomotor palsy and have utilization with endoscopic endonasal approaches to skull base tumors to protect cranial nerves?

Botulinum Toxins, Type A _gates_from_botulinum_toxins__type_a Muscle Relaxation _gates_to_muscle_relaxation _gates_from_muscle_relaxation Neuroprotection _gates_to_neuroprotection Oculomotor Nerve Diseases _gates_from_oculomotor_nerve_diseases BTX-A

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Experiment #00000062

NESCO-induced pyroptosis in the peritoneal microenvironment might be attenuated by the upregulation of 11-oxygenated androgens in the systemic circulation.

Endometriosis _gates_from_endometriosis Tumor Microenvironment _gates_to_tumor_microenvironment Androgens _gates_from_androgens _gates_to_endometriosis Disease Models, Animal _gates_from_disease_models__animal NESCO and Androgens

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