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Experiment #00000068
ALS; FUS; STMN2; TDP-43; protein translation; stress granule
Cell Nucleus
_gates_from_cell_nucleus
RNA Splicing
_gates_to_rna_splicing
_gates_from_rna_splicing
Protein Biosynthesis
_gates_to_protein_biosynthesis
_gates_from_protein_biosynthesis
Motor Neuron Disease
_gates_to_motor_neuron_disease
Protein Transport
_gates_from_protein_transport
Phase Transition
_gates_to_phase_transition
_gates_from_phase_transition
Cytoplasmic Granules
_gates_to_cytoplasmic_granules
_gates_from_cytoplasmic_granules
Stathmin
_gates_to_stathmin
DNA-Binding Proteins
_gates_from_dna_binding_proteins
_gates_from_stathmin
_gates_to_dna_binding_proteins
+14 more
View Results
Experiment #00000023
Does misfolded TDP43 affect Retinal Ganglion Cell STMN2 ability to repair in a similar way as what how it was shown to affect motor neurons with cryptic mis-splicing?
TDP-43 pathology
_gates_from_tdp_43_pathology
RNA Splicing
_gates_to_rna_splicing
_gates_from_rna_splicing
Stathmin 2
_gates_to_stathmin_2
Vitreous Body
_gates_to_vitreous_body
DNA-Binding Protein-43
_gates_from_dna_binding_protein_43
Retinal Ganglion Cells
_gates_to_retinal_ganglion_cells
Cell Nucleus
_gates_from_cell_nucleus
_gates_from_stathmin_2
Axonal Degeneration
_gates_to_axonal_degeneration
Axons
_gates_to_axons
_gates_from_axons
+11 more
View Results
Reference Abstract
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Source: PubMed
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