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Experiment #00000012

If a toxin with a thermodynamic affinity for Zinc GREATER THAN that of Glutamate AND LESS THAN that of RGNEF, under certain conditions a pathway exists wherein the toxin could shuttle synaptic retinal zinc to RGNEF, thus potentially ultimately resulting in the retinal TDP-43 proteinopathy seen in the retina post mortem in Sporadic Amyotrophic Lateral Sclerosis

Synaptic Zinc _gates_from_synaptic_zinc Receptors, Glutamate _gates_to_receptors__glutamate _gates_from_receptors__glutamate Zinc Dyshomeostasis in RGCs _gates_to_zinc_dyshomeostasis_in_rgcs _gates_from_zinc_dyshomeostasis_in_rgcs TDP-43 Proteinopathy _gates_to_tdp_43_proteinopathy

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