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Experiment #00000145
The use of cGAS-STING inhibitors (e.g., H151) and senotherapeutics, currently being explored for cancer and neurodegeneration, may provide a novel pharmacological path for rescuing sarcopenic muscle function.
Mitochondrial dysfunction
_gates_from_mitochondrial_dysfunction
DNA, Mitochondrial
_gates_to_dna__mitochondrial
_gates_from_dna__mitochondrial
cGAS-STING signaling
_gates_to_cgas_sting_signaling
_gates_from_cgas_sting_signaling
Cellular Senescence
_gates_to_cellular_senescence
STING Agonist
_gates_from_sting_agonist
Muscle, Skeletal
_gates_to_muscle__skeletal
+4 more
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Reference Abstract
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Source: PubMed
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