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PathMap Literature Based Discovery Engine
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Experiment #00000100
Hypothesis: Restored clearance of senescent neutrophils by tissue-resident macrophages limits organ aging
Aging
_gates_from_aging
Phagocytosis
_gates_to_phagocytosis
_gates_from_phagocytosis
Neutrophils
_gates_to_neutrophils
_gates_from_neutrophils
_gates_to_aging
Indoleacetic Acids
_gates_from_indoleacetic_acids
Pregnane X Receptor
_gates_to_pregnane_x_receptor
NF-E2-Related Factor 2
_gates_from_nf_e2_related_factor_2
Macrophages, Alveolar
_gates_to_macrophages__alveolar
_gates_from_macrophages__alveolar
Inflammation
_gates_to_inflammation
+10 more
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Experiment #00000082
Microbiota-derived acetate can alleviate neurological inflammation and neurodegeneration induced by hypoxia via the upregulation of brain-derived neurotrophic factor (BDNF).
Hypoxia
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Dysbiosis
_gates_to_dysbiosis
_gates_from_dysbiosis
Acetic Acid
_gates_to_acetic_acid
_gates_from_acetic_acid
Neuroinflammation
_gates_to_neuroinflammation
Brain-Derived Neurotrophic Factor
_gates_to_brain_derived_neurotrophic_factor
_gates_from_neuroinflammation
_gates_from_brain_derived_neurotrophic_factor
Neuroprotection
_gates_to_neuroprotection
Microglial Activation
_gates_to_microglial_activation
Neurodegenerative Diseases
_gates_to_neurodegenerative_diseases
+10 more
View Results
Reference Abstract
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Source: PubMed
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