PathMap Literature Based Discovery Engine

Share your Discovery:

Guaranteed to find unpublished literature based discoveries.

Clear Search

Experiment #00000138

Dietary butyrate from resistant starch may synergize with sulforaphane-driven Nrf2 activation and spermidine-mediated FAM134B ER-phagy in order to restore astrocytic EAAT2 membrane trafficking and potentially clear synaptic glutamate excitotoxicity in neurodegeneration. (Literature Based Discovery)

Starch, Resistant _gates_from_starch__resistant Butyrate _gates_to_butyrate _gates_from_butyrate NF-E2-Related Factor 2 _gates_to_nf_e2_related_factor_2 Sulforaphane _gates_from_sulforaphane Spermidine
View Results
Experiment #00000100

Hypothesis: Restored clearance of senescent neutrophils by tissue-resident macrophages limits organ aging

Aging _gates_from_aging Phagocytosis _gates_to_phagocytosis _gates_from_phagocytosis Neutrophils _gates_to_neutrophils _gates_from_neutrophils _gates_to_aging Indoleacetic Acids
View Results