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Experiment #00000105
Gap Analysis: There is no PubMed data showing wet lab data or analysis of TPD-43 proteinopathy found (or not found) in the Cochlear, Spiral, or Scarpa's Ganglion of Amyotrophic Lateral Sclerosis patient data post mortem.
Amyotrophic Lateral Sclerosis
_gates_from_amyotrophic_lateral_sclerosis
TDP-43 proteinopathy
_gates_to_tdp_43_proteinopathy
_gates_from_tdp_43_proteinopathy
Spiral Ganglion
_gates_to_spiral_ganglion
Peripheral Nerves
_gates_from_peripheral_nerves
_gates_to_amyotrophic_lateral_sclerosis
Noise-Induced Hearing Loss
_gates_from_noise_induced_hearing_loss
DNA-Binding Proteins
_gates_to_dna_binding_proteins
_gates_from_dna_binding_proteins
Autophagy
_gates_to_autophagy
_gates_from_autophagy
Hearing Disorders
_gates_to_hearing_disorders
+10 more
View Results
Experiment #00000022
Do Bulbar Amyotrophic Lateral Sclerosis patients have TDP43 proteinopathy in cochlear/spiral ganglion post mortem?
Ubiquilin-1
_gates_from_ubiquilin_1
TDP-43 Proteinopathies
_gates_to_tdp_43_proteinopathies
_gates_from_tdp_43_proteinopathies
Amyotrophic Lateral Sclerosis
_gates_to_amyotrophic_lateral_sclerosis
Disease Models, Animal
_gates_from_disease_models__animal
Cochlear Nucleus
_gates_to_cochlear_nucleus
_gates_from_cochlear_nucleus
TDP-43 proteinopathy
_gates_to_tdp_43_proteinopathy
_gates_from_amyotrophic_lateral_sclerosis
_gates_from_tdp_43_proteinopathy
Spiral Ganglion Neurons
_gates_to_spiral_ganglion_neurons
+8 more
View Results
Experiment #00000005
What are the biomarker differences in TDP-43 proteinopathy within the cerebellum and retina when comparing Sporadic Amyotrophic Lateral Sclerosis and c9orf72 affected Familial Amyotrophic Lateral Sclerosis? Are there any mutually exclusive biomarkers that can be deduced?
C9orf72 expansion
_gates_from_c9orf72_expansion
Dipeptide Repeats
_gates_to_dipeptide_repeats
_gates_from_dipeptide_repeats
Microglia
_gates_to_microglia
C9orf72 Protein
_gates_from_c9orf72_protein
Cerebellum
_gates_to_cerebellum
Sporadic ALS
_gates_from_sporadic_als
TDP-43 Proteinopathies
_gates_to_tdp_43_proteinopathies
Inclusion Bodies
_gates_to_inclusion_bodies
Amyotrophic Lateral Sclerosis
_gates_from_amyotrophic_lateral_sclerosis
Peptides
_gates_to_peptides
C9orf72 Expansion
Atrophy
_gates_to_atrophy
TDP-43 Proteinopathy
_gates_from_tdp_43_proteinopathy
Retinal Degeneration
_gates_to_retinal_degeneration
C9orf72 hexanucleotide repeat
_gates_from_c9orf72_hexanucleotide_repeat
Transcriptome
_gates_to_transcriptome
TDP-43 pathology
_gates_from_tdp_43_pathology
Retina
_gates_to_retina
+26 more
View Results
Reference Abstract
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Source: PubMed
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