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Experiment #00000004
Can the identified lysosomal-targeted acidic nanoparticles (AcNPs) or specific small-molecule chaperones effectively reverse established alpha-synuclein aggregation in chronic exposure models, and do they provide neuroprotection against subsequent environmental pollutant insults?
Lysosomal Storage Diseases
_gates_from_lysosomal_storage_diseases
alpha-Synuclein
_gates_to_alpha_synuclein
Alpha-synuclein aggregation
_gates_from_alpha_synuclein_aggregation
Molecular Chaperones
_gates_to_molecular_chaperones
Lysosomes
_gates_from_lysosomes
Neuroprotection
_gates_to_neuroprotection
α-synuclein aggregation
_gates_to____synuclein_aggregation
Nanoparticles
_gates_from_nanoparticles
Hydrogen-Ion Concentration
_gates_to_hydrogen_ion_concentration
Environmental Pollutants
_gates_from_environmental_pollutants
_gates_to_lysosomes
AcNPs/Chaperones
_gates_to_acnps_chaperones
_gates_from_acnps_chaperones
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