PathMap Literature Based Discovery Engine

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Experiment #00000078

Activated STING triggers inflammatory cytokines that directly drive astrocytic AQP4 depolarization; dampening this pathway restores the perivascular endfoot morphology necessary for glymphatic flow.

Metabolic Stress _gates_from_metabolic_stress DNA, Mitochondrial _gates_to_dna__mitochondrial _gates_from_dna__mitochondrial cGAS-STING Pathway _gates_to_cgas_sting_pathway _gates_from_cgas_sting_pathway Neuroinflammation _gates_to_neuroinflammation

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Experiment #00000020

Does age-related gut dysbiosis drive sarcopenia by activating the cGAS-STING inflammatory pathway to suppress satellite cell renewal?

Gastrointestinal Microbiome _gates_from_gastrointestinal_microbiome Inflammation _gates_to_inflammation _gates_from_inflammation cGAS-STING Pathway Activation _gates_to_cgas_sting_pathway_activation _gates_from_cgas_sting_pathway_activation Satellite Cells _gates_to_satellite_cells

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