PathMap Literature Based Discovery Engine

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Experiment #00000121

Exploration: The gut microbial metabolite 3-indolepropionic acid as a functional neuroprotective agent against intracerebral hemorrhage: integrating epidemiological screening with in vivo validation.

Dietary Tryptophan _gates_from_dietary_tryptophan Gut Microbiota _gates_to_gut_microbiota _gates_from_gut_microbiota 3-indolepropionic acid (3-IPA) _gates_to_3_indolepropionic_acid__3_ipa_ _gates_from_3_indolepropionic_acid__3_ipa_ Neuroprotection in ICH _gates_to_neuroprotection_in_ich
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Experiment #00000113

COPD Related Alveoli and Lung Microbiome Axis Restoration Hypothesis: The use of 'pre-digested' (fermented) plant-based nutritional additives as a means to circumvent the bioavailability paradox in patients with gut dysbiosis, effectively using botanical matrices as drug-delivery vehicles. Nucleotide supplementation may enhance the ability of A. muciniphila to modulate gut mucosal barrier integrity in hyperuricemia patients. *Akkermansia* possesses unique enzymes (β-N-acetylhexosaminidases) that allow it to colonize the mucosal layer and participate in mucin degradation.

Fermentation _gates_from_fermentation Bioavailability _gates_to_bioavailability _gates_from_bioavailability Homeostasis _gates_to_homeostasis Plant Preparations _gates_from_plant_preparations Probiotics
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Experiment #00000019

What is the role of 3-indolepropionic acid within the body, and what foods or nutrients may help replenish it if deficient?

Edible Grain _gates_from_edible_grain Clostridium sporogenes _gates_to_clostridium_sporogenes Gastrointestinal Microbiome _gates_from_gastrointestinal_microbiome 3-indolepropionic acid _gates_to_3_indolepropionic_acid _gates_from_3_indolepropionic_acid Signal Transduction
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